-Eleanor Roosevelt— Her husband had Polio so she had to FDR’s legwork for him…. she is considered the first woman president

-Susan B. Anthony— Famous suffragette

-Sally Hemings– The slave, who Jefferson had an affair with and supposedly fathered at least some of her children

-Edith Wilson— Woodrow Wilson’s second wife, who helped him hide the extent of his disability after suffering a debilitating stroke from the public, The Cabinet, and even The Vice President.

-Eleanor of Aquitaine— wife of Henry II who was stolen from the King of France, had 4 children and adopted a 5th, was imprisoned for 10 years (allowed out on Easter and Christmas) by her husband for no reason other that he hated her.

Oh and a few more obvious choices:

Mother Teresa

Hillary Clinton

Queen Elizabeth

Nancy Reagan

Jackie Kennedy

Jane Austen

Any of the Bronte Sisters (Charlotte, Emily, or Anne)

EDIT: Janis Joplin

Salma Hayek starred in a movie about her in 2002 called Frida.

Some books you could try are:

The Diary of Frida Kahlo: A self portrait by Frida Kahlo

Frida: A Biography of Frida Kahlo by Hayden Herrera

Frida Kahlo: Life and Work by Helga Prignitz-Poda

Hope this helped!!