1) To strike or punch someone or something (I hit Chuck in the face after he called me an aggressive goon.)

2) To make contact with an object, as in baseball. (Barry Bonds hit the ball out of the park for a homerun.)

3) In baseball, a hit occurs when the batter contacts the ball with his bat and succeeds in safely reaching first base. (Pete Rose has the most career hits in major league baseball history.)

4) A “hit” can also be a successful song, movie, play, etc, that achieves massive popularity. (The latest Harry Potter movie is a big hit.)

5) An paid assassination is also referred to as a “hit”. (The mafia boss ordered a hit on the witness that threatened to testify against him.)

There are other meanings as well….

If a guy wants to “hit that” it means he has targeted a woman he would like to have sex with.

“Hit don’t make no neverminds.”