Lacking a sense of direction is named by calling someone directionless, or by phrases such as chronically lost, hopelessly lost, and suffering aimlessness.

There really is no word for it since all humans have some sense of direction–even the lost.

Someone who is lost is “disoriented”–meaning not in possession of cardinal points by which to plot a course–literally not knowing where east is, where the sun rises–the “orient”…

NOUN:

A morally unprincipled person.

One who is predestined to damnation.

ADJECTIVE:

Morally unprincipled; shameless.

Rejected by God and without hope of salvation.

TRANSITIVE VERB:

rep·ro·bat·ed , rep·ro·bat·ing , rep·ro·bates

To disapprove of; condemn.

To abandon to eternal damnation. Used of God

-MM