Ex: Bob and Me went to school.

Me went to school. This is not correct.

I went to school. This is correct, so…Bob and I went to school.

Ex: They wont talk to Jane and me.

They won’t talk to me. This is correct, so the usage of “me” in the first sentence is acceptable.

Also whenever using yourself and another person, put the other person first. It sounds better.

Jane and me. Not: Me and Jane. Because Jane is not “mean”.

“Me” is the object form pronoun, and would be used when you are the object of the sentance rather than the subject. In the sentance “Are you talking to me?” “you” is the subject, and “me” is the object, so if we expand that sentance to “Are you talking to me and my sisters?” “me and my sisters” would be a more proper form, but it would be more common to say, “Are you talking to us?”

Jane Strauss has a bit more on this at the website below.

The ball rolled toward me and my sisters.

It is incorrect to use “me and my sisters” when it is in the subject of a sentence. For example:

Me and my sisters rolled the ball down the street.

That is incorrect grammar. The very simple rule to remember is – use “me” with a phrase like “me and my sisters” only when it is correct to use “me” alone: “The ball rolled toward me”. The same applies to “I”. Use “I” with a phrase like “I and my sisters” only when it is correct to use “I” alone: “I rolled the ball”.

Hope this helps.

I went to the store.

and one can say

my sisters went to the store.

hence, my sisters and I went to the store.

but you would never say

me went to the store, unless you are a caveman, or a public school graduate

For example, “He bought dinner for me and my sisters.”

It’s correct only if “me and my sisters” is the object of the sentence – that is, an action is being done to, for, or on “me and my sisters.” Another example is, “My dad bought presents for my mother and me.”

Otherwise, use “I” instead of “me.”

Your going to say I am going to the mall.

So you can’t use me and my sisters are going to the mall, it has to be my sisters and I are going to the mall.